Near-field interaction explains features of antiviral action of non-functionalized nanoparticles

Valeri Z Lozovski, Volodymyr S Lysenko and Natalia M Rusinchuk

Abstract

There are many experiments demonstrating antiviral activity of non-functionalised nanoparticles. However, there is no unified view on the interaction between the nanoparticles and viruses, which could explain all the features of this action. The idea of physical reasons of antiviral activities of non-functionalised nanoparticles against various viruses has been proposed previously and applied for explanation of our experimental results. As the features of antiviral action of nanoparticles are similar to some features of near-field interactions, the main reason of antiviral activities is supposed to be the near-field interaction between the virus and the nanoparticle. In the work the proposed mechanism is justified, described, discussed and applied for explanation of existed experimental results on antiviral activity of non-functionalised nanoparticles of different research groups. It is shown that the mechanism allows explaining various experimental results. Consequently, we demonstrate that the near-field interaction between the virus and the nanoparticles may be the main reason for antiviral action of the nanoparticles