Impact of physical and chemical parameters on the hydroxyapatite nanopowder synthesized by chemical precipitation method

Thi Thu Trang Pham, Thu Phuong Nguyen, Thi Nam Pham, Thi Phuong Vu, Dai Lam Tran, Hoang Thai and Thi Mai Thanh Dinh

Abstract

In this paper, the synthesis of hydroxyapatite (HAp) nanopowder was studied by chemical precipitation method at different values of reaction temperature, settling time, Ca/P ratio, calcination temperature, (NH₄)₂HPO₄ addition rate, initial concentration of Ca(NO₃)₂ and (NH₄)₂HPO₄. Analysis results of properties, morphology, structure of HAp powder from infrared (IR) spectra, x-ray diffraction (XRD), energy dispersive x-ray (EDX) spectra and scanning electron microscopy (SEM) indicated that the synthesized HAp powder had cylinder crystal shape with size less than 100 nm, single-phase structure. The variation of the synthesis conditions did not affect the morphology but affected the size of HAp crystals